Gpr177 Deficiency Impairs Mammary Development and Prohibits Wnt-Induced Tumorigenesis
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چکیده
منابع مشابه
Gpr177 Deficiency Impairs Mammary Development and Prohibits Wnt-Induced Tumorigenesis
Aberrant regulation of the Wnt pathway, essential for various developmental processes, is tightly linked to human breast cancers. By hijacking this evolutionary conserved signaling pathway, cancer cells acquire sustaining proliferation ability, leading to modification of physiologic properties necessary for tumor initiation and progression. An enormous wealth of knowledge on the importance of W...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0056644